• Nihon Kyobu Geka Gakkai Zasshi · Feb 1994

    Review Case Reports

    [Aortic valve replacement in a patient with chronic idiopathic thrombocytopenic purpura].

    • S Tanaka, S Ishihara, S Hara, and H Niinami.
    • Department of Cardiovascular Surgery, Saisekai Maebashi Hospital, Japan.
    • Nihon Kyobu Geka Gakkai Zasshi. 1994 Feb 1;42(2):297-301.

    AbstractWe reported a case of aortic valve replacement in a patient with chronic idiopathic thrombocytopenic purpura (ITP). We used high-dose intravenous gammaglobulin therapy (400 mg/kg/day) for five days to increase the platelet prior to the operation. The number of platelet was 8-10 x 10(4)/microliters at admission and it was increased to 23 x 10(4)/microliters before surgery. Aortic valve was replaced to SJM#21A prosthesis using cardiopulmonary bypass. The platelet was transfused after the bypass. Perioperative hemorrhage was moderate and postoperative course was uneventful. We believe that high-dose intravenous gammaglobulin therapy for ITP is effective to minimize perioperative hemorrhage for open heart surgery.

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