• Martina Studer, Eugen Boltshauser, Andrea Capone Mori, Alexandre Datta, Joel Fluss, Danielle Mercati, Annette Hackenberg, Elmar Keller, Oliver Maier, Jean-Pierre Marcoz, Gian-Paolo Ramelli, Claudia Poloni, Regula Schmid, Thomas Schmitt-Mechelke, Edith Wehrli, Theda Heinks, and Maja Steinlin.
• From University Children's Hospital Berne (M. Studer, E.W., T.H., M. Steinlin); Center for Cognition, Learning and Memory (M. Studer, T.H., M. Steinlin), University of Berne; University Children's Hospital Zürich (E.B., A.H.); Children's Hospital Aarau (A.C.M.); University Children's Hospital Basel (A.D.); University Children's Hospital Geneva (J.F.); Children's Hospital Neuchâtel (D.M.); Children's Hospital Chur (E.K.); Children's Hospital St. Gallen (O.M.); Children's Hospital Sion (J.-P.M.); Children's Hospital Bellinzona (G.-P.R.); University Children's Hospital Lausanne (C.P.); Children's Hospital Winterthur (R.S.); and Children's Hospital Lucerne (T.S.-M.), Switzerland.
• Neurology. 2014 Mar 4;82(9):784-92.

ObjectiveWe examined cognitive performance in children after stroke to study the influence of age at stroke, seizures, lesion characteristics, neurologic impairment (NI), and functional outcome on cognitive outcome.MethodsThis was a prospectively designed study conducted in 99 children who sustained an arterial ischemic stroke (AIS) between the age of 1 month and 16 years. All children underwent cognitive and neurologic follow-up examination sessions 2 years after the insult. Cognitive development was assessed with age-appropriate instruments.ResultsAlthough mean cognitive performance was in the lower normative range, we found poorer results in subtests measuring visuoconstructive skills, short-term memory, and processing speed. Risk factors for negative cognitive outcome were young age at stroke, seizures, combined lesion location (cortical and subcortical), as well as marked NI.ConclusionsWe recommend that all children with a history of AIS undergo regularly scheduled neuropsychological assessment to ensure implementation of appropriate interventions and environmental adjustments as early as possible.

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