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Expert Opin Investig Drugs · May 2011
EditorialFrom targeted therapy in ovarian cancer to personalizing therapy for ovarian cancer.
- César Gómez-Raposo, Marta Mendiola, Jorge Barriuso, David Hardisson, and Andrés Redondo.
- Expert Opin Investig Drugs. 2011 May 1;20(5):591-4.
AbstractEpithelial ovarian carcinoma (EOC) is the most important cause of gynecological cancer-related mortality in Western societies. The majority of patients with ovarian cancer present with advanced disease, and in this group of patients, the median survival time is only 3 years. New treatment approaches are, therefore, required to improve outcome in this disease. Two strategies have emerged with promising results: poly ADP-ribose polymerase enzyme (PARP) inhibitors and targeting angiogenesis. The challenge remains to develop a convenient and accurate method to identify patients likely to benefit from targeted therapy.
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