• Am. J. Physiol. Lung Cell Mol. Physiol. · Nov 2015

    Review

    Platelets in the pathogenesis of acute respiratory distress syndrome.

    • Hemang Yadav and Daryl J Kor.
    • Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; and.
    • Am. J. Physiol. Lung Cell Mol. Physiol. 2015 Nov 1; 309 (9): L915-23.

    AbstractPlatelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution of lung injury.Copyright © 2015 the American Physiological Society.

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