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Antimicrob. Agents Chemother. · Sep 2014
Randomized Controlled Trial Comparative StudyPreliminary study of colistin versus colistin plus fosfomycin for treatment of carbapenem-resistant Acinetobacter baumannii infections.
- Rujipas Sirijatuphat and Visanu Thamlikitkul.
- Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
- Antimicrob. Agents Chemother. 2014 Sep 1;58(9):5598-601.
AbstractNinety-four patients infected with carbapenem-resistant Acinetobacter baumannii were randomized to receive colistin alone or colistin plus fosfomycin for 7 to 14 days. The patients who received combination therapy had a significantly more favorable microbiological response and a trend toward more favorable clinical outcomes and lower mortality than those who received colistin alone. (This study has been registered at ClinicalTrials.gov under registration no. NCT01297894.).Copyright © 2014, American Society for Microbiology. All Rights Reserved.
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