• Jun Nakajima, Akiteru Goto, Shinichi Takamoto, Tomohiro Murakawa, Takeshi Fukami, and Masashi Kusakabe.
• Department of Cardiothoracic Surgery, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Tokyo 113-8655, Japan.
• Surg. Today. 2007 Jan 1;37(5):418-22.

AbstractSolitary lymphangioma of the lung is rare. We report a case of invasive lymphangioma of the lung, diagnosed in a 9-year-old girl who presented with intractable hemoptysis and a large pulmonary mass, 10 cm in diameter. We performed left lower lobectomy and lingular segmentectomy to remove the mass completely and the patient has been well for 3 years since. Pathologically, the mass was partly polycystic and partly solid. Irregular and dilated vascular and lymphatic vessels, as well as fibrosis of the interstitium, were spreading into the adjacent lung parenchyma, demonstrating their invasive nature. A new monoclonal antibody, D2-40, which reacts with lymphatic endothelium, proved useful for establishing the pathological diagnosis. We suggest that these pathological findings might be consistent with the intermediate type of localized lymphangioma of the lung and diffuse lymphangiomatosis.

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