• J. Neurol. Neurosurg. Psychiatr. · Apr 2005

    The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease.

    • M Maschke, P J Tuite, K Pickett, T Wächter, and J Konczak.
    • Sensorimotor Control Laboratory, Division of Kinesiology, University of Minnesota, Minneapolis, MN, USA. matthias.maschke@uni-essen.de
    • J. Neurol. Neurosurg. Psychiatr. 2005 Apr 1;76(4):569-71.

    BackgroundParkinson's disease is accompanied by deficits in passive motion and limb position sense.ObjectiveTo investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits.Methods And ResultsA passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON.ConclusionsSTN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function.

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