• Rev Mal Respir · Feb 2015

    Review

    [Bronchial thermoplasty in the treatment of severe adult asthma].

    • P Chanez, L-P Boulet, P-Y Brillet, G Joos, M Laviolette, R Louis, T Rochat, P Soccal, and M Aubier.
    • Inserm U1067 CNRS UMR 7333, service de pneumologie, AP-HM, Aix Marseille université, chemin des Bourrely, 13015 Marseille, France. Electronic address: pascal.chanez@univ-amu.fr.
    • Rev Mal Respir. 2015 Feb 1;32(2):97-109.

    AbstractBronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based treatment, the evaluation procedure of risks and benefits is different that for pharmaceutical products; safety aspects, regulatory requirements, study design and the assessment of the magnitude of effects may all be different. The mechanism of action and optimal patient selection need to be assessed further in rigorous clinical and scientific studies. This technique is in harmony with the development of personalised medicine in the 21st century. It should be developed further in response to the numerous challenges and needs not yet met in the management of severe asthma.Copyright © 2014 SPLF. Published by Elsevier Masson SAS. All rights reserved.

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