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Randomized Controlled Trial Clinical Trial
Effectiveness of tramadol as an analgesic in oral surgery.
- Rohana Kumara and Mathew Zacharias.
- Department of Stomatology, School of Dentistry, PO Box 647, Dunedin.
- N Z Dent J. 2002 Mar 1;98(431):9-11.
AbstractIn a randomised, double-blind, cross-over trial, 15 healthy, young patients undergoing surgical removal of bilateral, impacted, third-molar teeth received the analgesic tramadol 50 mg, as a single dose, either 2 hours prior or immediately before the surgical procedure. There were no differences in the post-operative pain levels or degree of trismus between the two methods of administration of tramadol (P > 0.05), suggesting absence of any pre-emptive analgesic effect for the drug in the dose studied. The prevalence of unwanted side effects such as nausea (37 percent) was high within the first 24 hours.
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