• Pacing Clin Electrophysiol · Aug 1993

    Randomized Controlled Trial Clinical Trial

    Randomized cross-over evaluation of two adaptive pacing algorithms for the termination of ventricular tachycardia.

    • M J Kantoch, M S Green, and A S Tang.
    • Department of Medicine, University of Ottawa, Ontario, Canada.
    • Pacing Clin Electrophysiol. 1993 Aug 1;16(8):1664-72.

    ObjectiveIn a randomized, cross-over study we evaluated the efficacy of rate adaptive constant cycle length (BURST) and autodecremental (RAMP) pacing for termination of sustained monomorphic ventricular tachycardia.MethodsAn external device capable of delivering the same types of antitachycardia pacing as the newer generation implantable cardioverter defibrillators was used. Thirty-one patients with ischemic and nonischemic cardiomyopathy and documented clinical ventricular tachycardia or ventricular fibrillation were examined during routine invasive electrophysiological studies. RAMP and BURST pacing were each attempted in 54 matched pairs of induced ventricular tachycardia. After a therapy was applied, the tachycardia was reinitiated and the other therapy applied during the second episode so that a total of 108 ventricular tachycardia episodes were studied.ResultsOverall efficacy of ventricular tachycardia pace termination was 69% and the time required to stop ventricular tachycardia was 14.1 +/- 11.3 seconds. The ability to terminate ventricular tachycardia by RAMP (72%) or BURST (65%) pacing was not significantly different. However, time to terminate ventricular tachycardia by RAMP (11.8 +/- 8.5 sec) was significantly shorter than by BURST (16.4 +/- 13.5), P < .001. Acceleration of ventricular tachycardia was uncommon with both pacing modes, 7/108 (7%). The ability to pace terminate ventricular tachycardia was cycle length dependent. The highest success was with ventricular tachycardia cycle length between 300 and 350 msec. The success rate decreased with faster and also slower ventricular tachycardia.Conclusions1. Rate adaptive pacing methods for ventricular tachycardia termination are effective and safe. 2. Autodecremental RAMP pacing afford quicker ventricular tachycardia termination than constant cycle length BURST pacing. 3. The ability to terminate ventricular tachycardia is cycle length dependent with cycle length range of 300-350 msec being most responsive to pace termination.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…