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J. Heart Lung Transplant. · Feb 2004
Case ReportsDobutamine-related asthma in a patient awaiting cardiac transplantation: the eosinophilic dilemma.
- Juan M Aranda, Greg Woo, Daniel F Pauly, Edgar Rodriguez, James A Hill, and Richard S Schofield.
- Division of Cardiovascular Medicine, Shands Hospital, University of Florida, Gainesville, Florida 32610, USA. arandjm@mail-cs.med.ufl.edu
- J. Heart Lung Transplant. 2004 Feb 1;23(2):260-1.
AbstractLong-term continuous intravenous inotrope infusion is frequently used as a pharmacologic bridge to cardiac transplantation in patients with end-stage congestive heart failure. We report a case of severe eosinophil-associated asthma after 6 weeks of therapy with the inotrope dobutamine in a patient awaiting cardiac transplantation. Review of the laboratory data revealed a steady increase in eosinophils during the period of treatment with dobutamine. Once the patient was switched to an alternative inotrope, milrinone, the eosinophil count returned to normal, and the asthma exacerbation resolved.
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