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TheScientificWorldJournal · Jan 2014
Randomized Controlled TrialSpinal anaesthesia with hyperbaric prilocaine in day-case perianal surgery: randomised controlled trial.
- Ozden Gorgoz Kaban, Dilek Yazicioglu, Taylan Akkaya, M Murat Sayin, Duray Seker, and Haluk Gumus.
- Ministry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
- ScientificWorldJournal. 2014 Jan 1;2014:608372.
BackgroundThe local anaesthetics used in day-case spinal anaesthesia should provide short recovery times. We aimed to compare hyperbaric prilocaine and bupivacaine in terms of sensory block resolution and time to home readiness in day-case spinal anaesthesia. MeTHODS: Fifty patients undergoing perianal surgery were randomized into two groups. The bupivacaine-fentanyl group (Group B) received 7.5 mg, 0.5% hyperbaric bupivacaine + 20 μg fentanyl in total 1.9 mL. The prilocaine-fentanyl group (Group P) received 30 mg, 0.5% hyperbaric prilocaine + 20 μg fentanyl in the same volume.ResultsTime to L1 block and maximum block was shorter in Group P than in Group B (Group P 4.6 ± 1.3 min versus Group B 5.9 ± 01.9 min, P = 0.017, and Group P 13.2 ± 7.5 min versus Group B 15.3 ± 6.6 min, P = 0.04). The time to L1 regression and S3 regression of the sensorial block was significantly shorter in Group P than in Group B (45.7 ± 21.9 min versus 59.7 ± 20.9 min, P = 0.024, and 133.8 ± 41.4 min versus 200.4 ± 64.8 min, P < 0.001). The mean time to home readiness was shorter for Group P than for Group B (155 ± 100.2 min versus 207.2 ± 62.7 min (P < 0.001)).ConclusionDay-case spinal anaesthesia with hyperbaric prilocaine + fentanyl is superior to hyperbaric bupivacaine in terms of earlier sensory block resolution and home readiness and the surgical conditions are comparable for perianal surgery.
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