• Takahshi Yamano, Takashi Kubo, Shigeho Takarada, Kohei Ishibashi, Kenichi Komukai, Takashi Tanimoto, Yasushi Ino, Hironori Kitabata, Kumiko Hirata, Atushi Tanaka, Toshio Imanishi, and Takashi Akasaka.
• Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan. akasat@wakayama-med.ac.jp
• J Am Soc Echocardiogr. 2010 Nov 1;23(11):1177-82.

BackgroundThe purpose of this study was to investigate the acute effect of right ventricular outflow tract (RVOT) pacing and right ventricular apex (RVA) pacing on synchronous ventricular activation and coronary flow dynamics.MethodsWe enrolled 20 consecutive patients who underwent electrophysiologic study. Echocardiographic study including two-dimensional tissue tracking imaging and Doppler guide wire examination was performed during RVOT pacing and RVA pacing.ResultsThe improvement of left ventricular radial dyssynchrony (99 ± 12 ms vs. 142 ± 16 ms, P < .001), time-averaged peak velocities of coronary blood flow (54 ± 18 cm/s vs. 47 ± 17 cm/s, P = .007), and coronary microvascular resistance index (2.0 ± 0.8 vs. 2.4 ± 1.1, P = .028) was observed with RVOT pacing compared with RVA pacing.ConclusionRVOT pacing might provide favorable effects on the left ventricular function and coronary flow dynamics over RVA pacing.Copyright © 2010 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.

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