• Andrew Jacovides, Mampedi Bogoshi, Larry A Distiller, Ehab Y Mahgoub, Mahomed Ka Omar, Ismail A Tarek, and Dalia B Wajsbrot.
• Midrand Medical Centre, Midrand, South Africa andrewjacovides110@gmail.com.
• J. Int. Med. Res. 2014 Aug 1; 42 (4): 1018-28.

ObjectiveTo determine the prevalence of diabetic peripheral neuropathic pain (DPNP) among South African adults with type 1 or type 2 diabetes.MethodsThis cross-sectional study recruited patients with diabetes from 50 institutional/private clinics. DPNP was diagnosed using Douleur Neuropathique 4 (DN4) questionnaire (score ≥4). Health-related quality-of-life (HRQoL) and sleep were assessed with EQ-5D and Daily Sleep Interference Scale (DSIS), respectively.ResultsPrevalence of DPNP was 30.3% (n = 1046). Risk of DPNP was significantly increased in people aged 50-64 years (odds ratio [OR] 1.71, 95% confidence intervals [CI] 1.21, 2.41), with diabetes for ≥10 years (OR 1.55, 95% CI 1.15, 2.08), female patients (OR 1.58, 95% CI 1.18, 2.12), and black patients (OR 1.71, 95% CI 1.19, 2.46). Mean ± SD EQ-5D and DSIS scores were 0.84 ± 0.16 and 0.83 ± 1.90, respectively, in participants without DPNP versus 0.64 ± 0.25 and 3.62 ± 2.96, respectively, in those with DPNP.ConclusionsDPNP is widely prevalent in South Africa. Despite its negative impact on HRQoL and sleep, DPNP is inadequately treated. DN4 is an easy-to-use, validated questionnaire that can be used widely as a DPNP screening tool in clinical practice.© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

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