• Charu Mahajan, Girija Prasad Rath, Parmod Kumar Bithal, Hemanshu Prabhakar, Rahul Yadav, and Surya Kumar Dube.
• Department of Neuroanaesthesiology, Neurosciences Center, Room No. 711, All India Institute of Medical Sciences, New Delhi 110029, India.
• J Anesth. 2010 Dec 1; 24 (6): 845-8.

PurposeVarious strategies have been proposed to reduce discomfort of pain after rocuronium injection. These studies have shown pretreatment of drugs such as fentanyl and lidocaine to be effective. In a prospective randomized study, we evaluated whether pretreatment with local warming at injection site using an air-warming device could effectively alleviate pain induced by rocuronium.MethodsNinety patients undergoing spinal surgeries were randomly divided into two groups: group C (control) and group T (treatment). Patients in group T were subjected to warming at 40°C for 1 min prior to injecting 1 ml (10 mg) of rocuronium at the site of venous access. Patients were then assessed for any discomfort and to quantify their discomfort on a 5-point scale.ResultsAge, sex, and weight were comparable between the two groups. Pain on rocuronium administration was reported by 88.9% patient in group C versus 66.7% in group T (p < 0.05). Severe pain was significantly less in group T (35.6% vs. 8.9%).ConclusionApplication of warmth over the vascular access prior to rocuronium administration effectively reduces injection-related pain.

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