• Anaesthesia · Dec 1996

    Randomized Controlled Trial Clinical Trial

    Pre-operative oral administration of morphine in day-case gynaecological laparoscopy.

    • R Rasanayagam and G Harrison.
    • Birmingham and Midlands Hospital for Women, Sparkhill.
    • Anaesthesia. 1996 Dec 1;51(12):1179-81.

    AbstractThe analgesic effect of morphine sulphate 10 mg by mouth given pre-operatively on pain after gynaecological laparoscopy was studied in a randomised, prospective, double-blind, placebo-controlled comparison. Two groups of 56 patients were studied one group undergoing diagnostic laparoscopy and the other laparoscopic sterilisation. All patients received a standard anaesthetic after premedication with morphine or placebo 1 h before the operation. Morphine premedication did not significantly influence postoperative pain as assessed on a visual analogue scale in either group and postoperative opioid consumption was unaffected. Premedication with morphine 10 mg orally does not significantly decrease pain after day-case gynaecological laparoscopy.

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