• Br J Anaesth · Sep 1998

    Randomized Controlled Trial Clinical Trial

    Does speed of intrathecal injection affect the distribution of 0.5% hyperbaric bupivacaine?

    • A Casati, G Fanelli, G Cappelleri, A Leoni, M Berti, G Aldegheri, and G Torri.
    • University of Milan, Department of Anaesthesiology, IRCCS H San Raffaele, Italy.
    • Br J Anaesth. 1998 Sep 1;81(3):355-7.

    AbstractWe have evaluated the influence of speed of intrathecal injection on lateral distribution of 0.5% hyperbaric bupivacaine. We studied 60 patients undergoing lower limb surgery who were placed in the lateral position with the operative side in the dependent position. After dural puncture (25-gauge Whitacre spinal needle), the needle aperture was turned towards the dependent side and 0.5% hyperbaric bupivacaine 8 mg was injected randomly at a rate of 0.02 ml s-1 (group slow, n = 30) or 0.25 ml s-1 (group fast, n = 30). Lateral position was maintained for 15 min while a blinded observer recorded loss of pinprick sensation and degree of motor block on both surgical and non-surgical sides. There were no differences between the groups. Forty-five minutes after patients were turned to the supine position, spinal anaesthesia was unilateral in 17 patients in group slow (56%) and in 13 patients in group fast (43%). We conclude that using extremely low speeds for intrathecal injection were not clinically advantageous in obtaining unilateral spinal anaesthesia.

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