• Southern medical journal · Jul 2009

    Case Reports

    Pericardial involvement as a rare manifestation of hypereosinophilic syndrome.

    • Shevyll Arvie Tan and Abhijit Duggal.
    • Western Reserve Care System, Northside Medical Center, Youngstown, OH, USA. sstan@healtheast.org
    • South. Med. J. 2009 Jul 1;102(7):751-3.

    AbstractA 56-year-old female with idiopathic hypereosinophilic syndrome who presented with chest tightness, dyspnea and new-onset atrial fibrillation is reported. Work up revealed significant peripheral eosinophilia, pericarditis, and a pericardial effusion with tamponade physiology. Pericardiocentesis revealed predominant eosinophils (88%) in the pericardial fluid. After initial stabilization, pericardial effusion reaccumulated with persistence of marked eosinophilia. A diagnosis of idiopathic hypereosinophilic syndrome was made, and she was started on prednisone with a dramatic resolution of her clinical symptoms.

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