• Clinical pediatrics · Oct 2008

    Review

    Cutaneous mastocytosis: a review focusing on the pediatric population.

    • Laura D Briley and Charles M Phillips.
    • PGY3- Department of Dermatology, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27834, USA. Brileyla@ecu.edu
    • Clin Pediatr (Phila). 2008 Oct 1;47(8):757-61.

    AbstractCutaneous mastocytosis can be divided into 4 different clinical variants--urticaria pigmentosa, solitary mastocytoma, diffuse cutaneous mastocytosis, and telangiectasia macularis eruptiva perstans. Skin findings are often accompanied by symptoms secondary to mast cell release of mediators. These symptoms can be both localized to the skin lesion and systemic because of the release of mediators into the bloodstream. The majority of pediatric cases of cutaneous mastocytosis show a good prognosis with gradual resolution of both symptoms and skin lesions. This article will review each of the 4 clinical presentations focusing on pediatric-onset of disease while reviewing the literature.

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