• Anesteziol Reanimatol · May 1996

    Comparative Study

    [The risk factors for the development of the multiple organ failure syndrome in destructive pancreatitis].

    • I P Vereshchagin, A V Zolotarev, and D I Kuznetsov.
    • Anesteziol Reanimatol. 1996 May 1(3):43-5.

    AbstractThe role of neutrophil leukocytes in the development of the polyorgan failure syndrome during an unfavorable course of destructive pancreatitis is discussed. The examinations of 52 patients demonstrated a high correlation of neutrophil functional activity tests (nitroblue tetrazolium reduction test and leukocyte-platelet aggregation) and disorders of microcirculation and hepatorenal involvement (detected clinically and by laboratory tests). The "critical mass" of leukocytosis has been estimated: at least 18 . 10(9)/liter, at which the risk of polyorgan failure appreciably increases. The authors discuss the advisability of selective cytopheresis in a complex of intensive care for critical states involving endogenous poisoning and leukocytosis.

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