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Postgraduate medicine · Apr 1991
Review Case ReportsNeuroleptic malignant syndrome. When levodopa withdrawal is the cause.
- C Rainer, N A Scheinost, and E J Lefeber.
- Department of Medicine, Good Samaritan Hospital, Phoenix, AZ 85006.
- Postgrad Med. 1991 Apr 1;89(5):175-8, 180.
AbstractNeuroleptic malignant syndrome has been described in patients receiving dopamine antagonists and in a few patients after withdrawal of dopaminergic antiparkinson therapy. Complications affect almost all organ systems and can be life-threatening. Most patients have fever, altered level of consciousness, bradykinesia, and rigidity. Treatment includes withdrawal of the causative agent and supportive therapy for complications. When withdrawal of a dopaminergic medication is the suspected cause, the agent should be reinstated.
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