• A K Brahma, S Shah, V F Hillier, D McLeod, T Sabala, A Brown, and J Marsden.
• Royal Eye Hospital, Manchester, United Kingdom.
• J Accid Emerg Med. 1996 May 1;13(3):186-8.

ObjectiveTo assess the analgesic effects of a topical non-steroidal anti-inflammatory agent, flurbiprofen 0.03%, during healing after superficial corneal injuries.Methods401 patients treated for corneal abrasion in a five month period were randomly allocated to one of four treatment groups: polyvinyl alcohol alone (control), homatropine 2%, flurbiprofen 0.03%, or homatropine 2% followed by flurbiprofen 0.03%. Treatments were given for 48 h. Ocular pain was recorded on a visual analogue scale by the patients over the first 24 h, and use of oral analgesics was also recorded. Usable responses were received from 224 patients (55.8%).ResultsPatients treated with flurbiprofen had significantly lower pain scores for the 24 h duration of the study than controls (P < 0.05).ConclusionsFlurbiprofen eye drops provide more effective pain relief than traditional treatments for superficial corneal injuries.

35 keywords...

hide…