• S. Afr. Med. J. · Jul 2012

    The spread of carbapenem-resistant Enterobacteriaceae in South Africa: risk factors for acquisition and prevention.

    • Adrian Brink, Jennifer Coetzee, Cornelis Clay, Craig Corcoran, Johan van Greune, J D Deetlefs, Louise Nutt, Charles Feldman, Guy Richards, Patrice Nordmann, and Laurent Poirel.
    • Department of Clinical Microbiology, Ampath National Laboratory Services, Milpark Hospital, Johannesburg, South Africa. brinka@ampath.co.za
    • S. Afr. Med. J. 2012 Jul 1;102(7):599-601.

    AbstractNew, effective antibiotics are only likely to become available in 15 - 20 years. To prevent deaths from untreatable Gram-negative infections in South Africa, the rights of any doctor, whether in general or in hospital practice, to indiscriminately prescribe whatever antibiotic they wish, and in whatever fashion, must be challenged. Furthermore, although prevention of the emergence and subsequent spread of carbapenem-resistant Enterobacteriaceae (CRE) has focused on acute and chronic care facilities and inter alia on antibiotic exposure in these institutions, CRE may soon become an issue within entire communities, highlighting a role for public health authorities in CRE prevention efforts.

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