• J Palliat Med · Oct 2009

    Review

    The role of fentanyl in cancer-related pain.

    • Eric Prommer.
    • Department of Hematology/Oncology/Palliative Care, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. prommer.eric@mayo.edu
    • J Palliat Med. 2009 Oct 1;12(10):947-54.

    AbstractFentanyl is a lipophilic, short-acting, synthetic opioid with a piperidine chemical structure. Fentanyl is an effective analgesic for cancer pain, and newer formulations such as the transmucosal and buccal forms have shown efficacy for the management of cancer-related breakthrough pain. This article reviews the pharmacodynamics, pharmacology, and clinical efficacy for this new option in treating moderate to severe pain.

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