• Curr Allergy Asthma Rep · Jan 2003

    Review

    The role of epinephrine in the treatment of anaphylaxis.

    • Anne K Ellis and James H Day.
    • Division of Allergy, Kingston General Hospital, 76 Stuart Street, Kingston, ON K7L 2V7, Canada. ellisa@kgh.kari.net
    • Curr Allergy Asthma Rep. 2003 Jan 1;3(1):11-4.

    AbstractEpinephrine is the cornerstone of anaphylaxis management. Its administration should be immediate upon evidence of the occurrence of anaphylaxis. Delays in administration may be fatal. The most appropriate administration is 0.3 to 0.5 mL of 1:1000 dilution intramuscularly for adults and 0.01 mg/kg for children, given in the lateral thigh. Patients with known anaphylactic reactivity should be prescribed an epinephrine auto-injector to be carried at all times for treatment of potential recurrences. Education of the patient or parent regarding the proper use of this tool is paramount.

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