• Rev Stomatol Chir Maxillofac · Feb 2012

    Clinical Trial

    [Botulinum toxin A: analgesic treatment for temporomandibular joint disorders].

    • C Denglehem, J-M Maes, G Raoul, and J Ferri.
    • Département Universitaire de Chirurgie Maxillo-Faciale et Stomatologie, Hôpital Roger-Salengro, CHRU de Lille, boulevard du Professeur-Émile-Laine, 59000 Lille, France. denglehem@gmail.com
    • Rev Stomatol Chir Maxillofac. 2012 Feb 1;113(1):27-31.

    IntroductionPain, along with clicking, sub-luxation, and blocking, is one of the main symptoms for patients presenting with temporomandibular joint disorders. We assessed the effectiveness of botulinum toxin A (BOTOX(®), Allergan) as analgesic treatment for temporomandibular joint disorders.Patients And MethodTwenty-six patients with chronic pain linked to temporomandibular joint disorders were prospectively assessed. Botulinum toxin A was injected in masseter and temporalis muscles. Follow-up parameters, at one and three months, were: measuring mouth opening and diduction, muscle tenderness and pain using a visual analogue scale.ResultsThere was a significant (P<0.0001) decrease of pain, an increased mouth opening, and diduction at three months. Seventy percent of the patients felt less muscle tenderness. The patient felt his psychological state had improved and so did his family.DiscussionBotulinum toxin A significantly decreases pain and improves movements of patients presenting with temporomandibular joint disorders. The effects are prolonged three months after the injection.Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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