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- A Eser, F Thalhammer, F Burghuber, C Högenauer, F Stockenhuber, C Wenisch, K Widhalm, and W Reinisch.
- Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Österreich.
- Z Gastroenterol. 2012 Oct 1;50(10):1089-95.
AbstractBetween 5 and 49% of patients treated with antibiotics suffer from diarrhoea. Principally all microbial agents can cause diarrhoea, especially oral agents like cephalosporines, clindamycin, broad-spectrum penicillins, and quinolones of the 3 rd and 4th generation. Manifestations of antibiotic-associated diarrhoea range from mild self-limiting forms to severe life-threatening courses. The potentially most severe form of antibiotic-associated diarrhoea is caused by Clostridium diffcile accounting for approx. 25 % of antibiotic-associated diarrhoea. In the past two decades a broad spectrum of different probiotic strains has been evaluated for the primary prevention of antibiotic-associated diarrhoea in children and adults. Based on their efficacy and clinical data, different levels of evidence and recommendations are emerging on the preventive use of probiotics in antibiotic-associated diarrhoea.© Georg Thieme Verlag KG Stuttgart · New York.
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