• Rebecca S Chick, James K Glisson, and Samuel Pierce.
• School of Medicine, University of Mississippi Medical Center, Jackson 39216, USA.
• J Miss State Med Assoc. 2010 Nov 1;51(11):317-20.

ObjectivesWe describe a case of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infection leading to bilateral cavernous sinus thrombosis (CST) and subsequent left eye blindness in a previously healthy, immunocompetent woman. A secondary objective is to document all published cases of MRSA induced CST.Data Source And Study SelectionTo identify all relevant publications on MRSA-induced CST in adults.ResultsSeven publications were included in this review describing patients age 19 or older. Together, with the case included in this publication, a total of 8 cases of MRSA induced CST have been documented since 2003. Of interest, to our knowledge this is the first reported case of CA-MRSA CST temporally associated with nasal H1N1 vaccination.ConclusionIn selecting empiric antibiotic coverage for septic CST, the practitioner should use antibiotics that are active against CA-MRSA to help prevent morbidity and mortality.

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