• Nora Hilda Segura Méndez, María de la Luz Barragán Estrada, María de Lourdes Paredes Delgado, Augusto Bernardo Torres Salazar, Lidia Angélica Betancourt Hernández, Martín Canizales Cobos, Erika Murillo Gómez, Luis Enrique Martínez Hernández, and Alejandra Mora Nieto.
• Médica adscrita al servicio de Alergia e Inmunología Clinica, Hospital de Especialidades Bernardo Sepúlveda, Centro Médico Nacional Siglo XXI, IMSS.
• Rev Alerg Mex. 2006 Jan 1;53(1):30-3.

AbstractThe laryngeal amyloidosis is an uncommon disease accounting for 1% of all benign lesions of larynx. The commonest symptom is the dysphonia, sometimes accompanied by stridor, laryngeal globus sensation, dysphagia and, in rare occasions, cough, dyspnea and hemoptysis, specially when the tracheobronchial tree is also affected. This paper describes the case of a 30-year-old female patient, whose main symptoms were progressive dysphonia and dyspnea, admitted at allergy service to rule out asthma. The respiratory function tests showed obstruction in the medium and small caliber ways without reversibility with salbutamol. Biopsies of ventricular band, vocal cord and arytenoid stained with positive Congo red for amyloid tissue, established the laryngeal amyloidosis diagnosis. The complementary studies to rule out amyloid tissue in the remaining tracheobronchial tree were negative. Dyspnea had characteristics of laryngeal origin, caused by a pulmonary ventilation disorder provoked by the difficult arrival of air to alveoli, which caused the decreased partial pressure of oxygen and CO2.

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