• Yasushi Miyagi, Tsuyoshi Okamoto, Takato Morioka, Shozo Tobimatsu, Yoshitaka Nakanishi, Kazuyuki Aihara, Kimiaki Hashiguchi, Nobuya Murakami, Fumiaki Yoshida, Kazuhiro Samura, Shinji Nagata, and Tomio Sasaki.
• Division of Digital Patient, Digital Medicine Initiative, Kyushu University, Higashi-ku, Fukuoka, Japan. yamiyagi@digital.med.kyushu-u.ac.jp
• Stereotact Funct Neurosurg. 2009 Jan 1;87(4):211-8.

AimsSpectral analysis of local field potential (LFP) recorded by deep brain stimulation (DBS) electrode around the subthalamic nucleus (STN) in patients with Parkinson's disease was performed.MethodsThe borders of the STN were determined by microelectrode recording. The most eligible trajectory for the sensorimotor area of the STN was used for LFP recording while advancing the DBS electrode.ResultsThe low-frequency LFP power (theta- to beta-band) increased from a few millimeters above the dorsal border of the STN defined by microelectrode recording; however, the low-frequency power kept the same level beyond the ventral border of the STN. Only high beta-power showed close correlation to the dorsal and ventral borders of the STN.ConclusionsA spectral power analysis of LFP recording by DBS electrode helps with the final confirmation of the dorsal and ventral borders of the STN of Parkinson's disease in DBS implantation surgery.Copyright 2009 S. Karger AG, Basel.

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