• Pediatr. Infect. Dis. J. · Aug 2012

    Case Reports

    Leukoreduction in patients with severe pertussis with hyperleukocytosis.

    • Gonzalo Oñoro, Alberto García Salido, Ignacio Mastro Martínez, Beatriz Cabeza, María Gillén, and Amelia Martínez de Azagra.
    • Pediatric Intensive Care Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. gonorootero@hotmail.com
    • Pediatr. Infect. Dis. J. 2012 Aug 1;31(8):873-6.

    AbstractWhen pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.

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