Combined factor V and VIII deficiency is a rare inherited autosomal recessive single gene disorder commonly seen in the Middle East. Although the factor levels are between 5-30%, several authors have reported that these patients are more prone to bleeding compared to those having an isolated factor deficiency with the same levels. We report an eight-year-old boy with factor V and VIII deficiency who underwent a successful circumcision using desmopressin (DDAVP).
Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Turkey.
Turkish J Pediatr. 2002 Apr 1;44(2):146-7.
AbstractCombined factor V and VIII deficiency is a rare inherited autosomal recessive single gene disorder commonly seen in the Middle East. Although the factor levels are between 5-30%, several authors have reported that these patients are more prone to bleeding compared to those having an isolated factor deficiency with the same levels. We report an eight-year-old boy with factor V and VIII deficiency who underwent a successful circumcision using desmopressin (DDAVP).