• Prog Neurol Surg · Jan 2012

    Review

    γ knife radiosurgery of other brain metastases.

    • Douglas Kondziolka, Ajay Niranjan, Hideyuki Kano, John C Flickinger, and L Dade Lunsford.
    • Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA. kondds@upmc.edu
    • Prog Neurol Surg. 2012 Jan 1;25:190-200.

    AbstractWe evaluated the role of Gamma Knife stereotactic radiosurgery in the multidisciplinary management of brain metastases ovarian and endometrial, prostate, thyroid, sarcoma, or unknown primary cancers. From a series of over 3,000 patients who had Gamma Knife radiosurgery for brain metastases we reviewed indications and outcomes in patients with less common cancer types. All tumor types responded favorably to radiosurgery. Patients with male and female genitourinary primaries tended to develop brain metastases late in their course and did worse. Patients with thyroid metastases appear to live much longer with a more indolent course. Radiosurgery is an effective and safe minimally invasive option for patients with brain metastases from these less common primary origins.Copyright © 2012 S. Karger AG, Basel.

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