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- A Billing, R M Arendt, H Arnoldt, and F W Schildberg.
- Chirurgische Klinik und Poliklinik, Ludwig-Maximilians-Universität, München.
- Langenbecks Arch Chir Suppl Kongressbd. 1997 Jan 1;114:508-12.
AbstractNecrotizing fasciitis has changed considerably over time. The disease used to be due to group A streptococci and affected otherwise quite healthy or traumatized subjects. Today we see multibacterial infections in polymorbid or immunocompromised patients. Rapid and resolute surgery is of critical prognostic value. Early clinical recognition may be difficult. Sometimes frozen-section biopsy proves helpful. Septic immune response and organ failure develop rapidly in these patients. After vigorous staged necrosectomy, extensive plastic reconstruction is mostly required.
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