• Arq Neuropsiquiatr · Sep 2005

    Case Reports

    Dexmedetomidine for awake craniotomy without laryngeal mask.

    • Antonio Nogueira de Almeida, Cristiane Tavares, Adriana Tibano, Seigi Sasaki, Kazuco Nakai Murata, and Raul Marino.
    • Instituto Neurológico de São Paulo, Hospital São Joaquim, Real e Benemérita Sociedade Portuguesa de Beneficência, São Paulo, SP, Brasil. almeidaan@globo.com
    • Arq Neuropsiquiatr. 2005 Sep 1;63(3B):748-50.

    ObjectiveThis paper reports the use of dexmedetomidine in three epileptic patients with cavernous angiomas that underwent awake surgery in order to map their speech areas.MethodLoading dose of dexmedetomidine varied from 1 microg/Kg/h to 3 microg/Kg/h over 20 minutes and maintenance dose from 0.4 microg/Kg/h to 0.8 microg/Kg/h.ResultsThere was no occurrence of hemodynamic instability, convulsions or respiratory depression. Patients tolerated well the procedure.ConclusionDexmedetomidine was useful for awake craniotomy as it decreased patients level of consciousness but did not produce agitation. Laryngeal mask was not necessary to keep air ventilation.

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