• Can J Emerg Med · Nov 2003

    Acute allergic reaction due to the administration of fibrinolytic therapy for ST-segment elevation myocardial infarction: case report and discussion.

    • Geoff C Mills, Robert T Arntfield, and Robert J Sedran.
    • University of Western Ontario CCFP-EM Residency Program, London, Ontario, Canada.
    • Can J Emerg Med. 2003 Nov 1;5(6):421-3.

    AbstractAlthough a rare phenomenon, acute allergic reactions to fibrinolytic and heparin therapy have been described in the literature. We report the case of a 63-year-old woman who experienced a severe anaphylactic reaction while undergoing fibrinolytic therapy with tissue plasminogen activator for an ST-segment elevation myocardial infarction. Overall outcome was successful, but patient morbidity was increased because of the reaction and the subsequent therapy administered.

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