• Siriwan Tangjitgamol, Benjamin O Anderson, Hui Ti See, Chawalit Lertbutsayanukul, Nakarin Sirisabya, Tarinee Manchana, Arunachalam Ilancheran, Khai Mun Lee, Siew Eng Lim, Yin-Nin Chia, Efren Domingo, Young-Tak Kim, Chyong-Huey Lai, Ahmad Zailani Hatta Mohd Dali, Wisit Supakapongkul, Sarikapan Wilailak, Eng-Hseon Tay, John Kavanagh, and Asian Oncology Summit.
• Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration Medical College and Vajira Hospital, Bangkok, Thailand.
• Lancet Oncol. 2009 Nov 1;10(11):1119-27.

AbstractEndometrial cancer is one of the gynaecological cancers that carries good overall prognosis because it is often detected at early stages of disease. The International Federation of Gynecology and Obstetrics replaced clinical staging with surgical staging in 1988 and updated the system in 2009. Controversies remain regarding the recommended screening protocol for women with a high risk of endometrial cancer, the role and benefit of retroperitoneal lymph-node dissection, the necessity of ovarian resection, the benefit and type of adjuvant radiation therapy, and the safety of hormone-replacement therapy after treatment. This article reviews the available evidence for optimum management of endometrial cancer and how management strategies can be applied in Asian countries with different levels of health-care resource availability and economic development. An overview of the literature for endometrial-cancer screening, diagnosis, and management is discussed. Consensus statements are formulated on the basis of basic, limited, enhanced, and maximum health-care resource availability, using the framework provided by the Breast Health Global Initiative.

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