• Clin Respir J · May 2016

    Case Reports

    The successful treatment of refractory respiratory failure due to miliary tuberculosis: Survival after prolonged extracorporeal membrane oxygenation support.

    • Sung-Jin Nam and Young-Jae Cho.
    • Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Kosin University, Busan, Republic of Korea.
    • Clin Respir J. 2016 May 1; 10 (3): 393-9.

    AbstractAcute respiratory distress syndrome (ARDS) has high morbidity and mortality. Although uncommon, pulmonary tuberculosis (TB) can cause ARDS in patients with extensive pulmonary parenchymal involvement. Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an accepted alternative option in refractory hypoxemic respiratory failure. It may normalize gas exchange and allow lung rest, avoiding ventilator induced lung injury. We report the case of a 44-year-old woman who developed ARDS secondary to pulmonary TB. Despite anti-TB treatment and mechanical ventilation, patient had persistent refractory hypoxemia. In order to prevent further lung injury, VV-ECMO support was performed for 73 days. Although the patient experienced several complications, patient was successfully managed on VV-ECMO. VV-ECMO support, in combination with anti-TB drugs, is a useful tool in the treatment of ARDS with refractory hypoxemia caused by miliary TB. © 2016 John Wiley & Sons Ltd.

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