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Ugeskrift for laeger · Mar 2009
[Brain injury marker S100B can reduce the use of computer tomography in minor head injuries--secondary publication].
- Jtiaocnob Bertram Springborg, Johan Undén, Tor Ingebrigtsen, and Bertil Romner.
- Neurokirurgisk Klinik, Rigshospitalet, DK-2100 København Ø. jacob.springborg@rh.regionh.dk
- Ugeskr. Laeg. 2009 Mar 16;171(12):978-81.
AbstractThe risk of acute intracranial complications after minor head injury (MHI) is low. Despite this, computed tomography (CT) is generally recommended with clinical observation as a secondary option. Both options have disadvantages. Clinical studies have shown the potential advantages of using the biomarker S100B. The specificity of S100B is low, but a high sensitivity for brain damage results in a clinically useful, high negative predictive value (NPV). Integration of S100B into existing management routines can reduce the need for CT scans or admission by over 30%.
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