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- Doralina L Anghelescu, Lauren C Rakes, Jack R Shearer, and George B Bikhazi.
- Pain Management Service, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. doralina.anghelescu@stjude.org
- AANA J. 2011 Jun 1;79(3):238-42.
AbstractEmergence agitation (EA) can be a distressing side effect of pediatric anesthesia. We retrospectively reviewed the records of 7 pediatric oncology patients who received low-dose ketamine in conjunction with propofol for total intravenous anesthesia (TIVA) repeatedly for radiation therapy. EA signs were observed in all 7 patients in association with propofol TIVA but did not recur in any of 123 subsequent anesthetics sessions during which low-dose ketamine was added to propofol. Based on this experience, we suggest that low-dose ketamine added to propofol may be associated with prevention of EA in children with a history of EA with propofol TIVA.
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