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Sarcoidosis Vasc Dif · Oct 2011
Case ReportsSuccessful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus.
- M Faehling, S Frohnmayer, M Leschke, B Trinajstic-Schulz, J Weber, and F Liewald.
- Klinik für Kardiologie und Pneumologie, Klinikum Esslingen, Esslingen; 2Lungenfacharztpraxis, Esslingen. m.faehling@klinikum-es.de
- Sarcoidosis Vasc Dif. 2011 Oct 1;28(2):153-5.
AbstractWe report a successful pregnancy in a patient with longstanding LAM on treatment with sirolimus. During temporary discontinuation fo sirolimus in early pregnancy, lung function declined but recovered after resumption of sirolimus. Pregnancy was complicated by a persistent pneumothorax which was treated surgically postnatally. The child has had a normal development despite exposure to low dose sirolimus intermittently during early embryonal and mid-fetal life.
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