• Ali Al-Khafaji and David T Huang.
• Abdominal Organs Transplant Intensive Care Unit, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA. alkhafajia2@upmc.edu
• Crit. Care Med. 2011 May 1;39(5):1157-66.

ObjectivesTo review the management of complications related to end-stage liver disease in the intensive care unit. The goal of this review is to address topics important to the practicing physician.Data SourcesWe performed an organ system-based PubMed literature review focusing on the diagnosis and treatment of critical complications of end-stage liver disease. DATA SYNTHESIS AND FINDINGS: When available, preferential consideration was given to randomized controlled trials. In the absence of trials, observational and retrospective studies and consensus opinions were included. We present our recommendations for the neurologic, cardiovascular, pulmonary, gastrointestinal, renal, and infectious complications of end-stage liver disease.ConclusionsComplications related to end-stage liver disease have significant morbidity and mortality. Management of these complications in the intensive care unit requires awareness and expertise among physicians from a wide variety of fields.

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