• Int. J. Cardiol. · Jan 2009

    Letter Case Reports

    Patent foramen ovale and ascending aortic aneurysm with platypnea-orthodeoxia syndrome.

    • Francesco Patanè, Salvatore Patanè, Edoardo Zingarelli, Fabrizio Sansone, and Antonio Campanella.
    • Int. J. Cardiol. 2009 Jan 24;131(3):e90-1.

    AbstractPlatypnea-orthodeoxia is a rare syndrome characterized by dyspnea induced by the upright position and relieved by supine position and an arterial deoxygenation increased by the upright position which improves during recumbency. Several anatomical factors that can alter the atrial anatomy and facilitate shunting through an interatrial defect have been related with this syndrome. In many cases, this syndrome has been associated with patent foramen ovale and right-to-left shunt. Rarely platypnea-orthodeoxia syndrome has been described associated with an aortic aneurysm too. We present a case of platypnea-orthodeoxia syndrome in a 76-year-old Italian man with patent foramen ovale and ascending aortic aneurysm.

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