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Int J Gynaecol Obstet · Oct 2004
Randomized Controlled Trial Clinical TrialHigh and low dose oxytocin in augmentation of labor.
- A Jamal and R Kalantari.
- OB/GYN Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. af_jamal@yahoo.com
- Int J Gynaecol Obstet. 2004 Oct 1;87(1):6-8.
ObjectiveTo compare the efficacy and safety of high dose oxytocin in the augmentation of labor.MethodTwo hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either a low dose protocol (1.5 microm/min initially, increased by 1.5 microm/min every 30 min) or a high dose protocol (4.5 microm/min initially, increased by 4.5 microm/min every 30 min).ResultsHigh dose of oxytocin was associated with a significant shortening of labor 4 (1.10-10) vs. 6 (1-10) h, p<0.0001 without a significant difference in cesarean delivery rate, neonatal and maternal outcome.ConclusionThe use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.
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