• Adv Clin Exp Med · May 2012

    Review

    Tryptase in diagnosing adverse suspected anaphylactic reaction.

    • Grazyna Michalska-Krzanowska.
    • Division of Anesthesiology and Intensive Care, 111th Military Hospital with Outpatient Clinic, Poznań, Poland. grazyna195@op.pl
    • Adv Clin Exp Med. 2012 May 1;21(3):403-8.

    AbstractDetermination of serum mast cell tryptase (MCT) is becoming more widely used in diagnosing allergic reactions involving mast cells. It can help evaluate the allergenic effects of drugs administered during anesthesia and the perioperative period. Until now, data about the role of tryptase in the body has not been clarified yet. Patients with elevated MCT levels should undergo further testing to find out the causative agent of a potential allergic reaction. Patients with normal tryptase concentration should also undergo further diagnosis if they manifest clinical symptoms of a severe anaphylactic reaction.

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