• Medical hypotheses · Sep 1995

    On the nature of the link between malignant hyperthermia and exertional heatstroke.

    • L Bourdon and F Canini.
    • Centre de Recherces du Service de Santé des Armées, La Tronche, France.
    • Med. Hypotheses. 1995 Sep 1;45(3):268-70.

    AbstractMalignant hyperthermia (MH) is a rare myopathy inducing severe accident when carriers are exposed to triggering agents. MH susceptibility (MHS) is assessed by pharmacological tests performed on muscle strips. Exertional heat stroke (EHS) is a severe accident occurring during long and strenuous exercise. It has been observed that numerous EHS patients are susceptible to MH according to pharmacological tests. Because most of those EHS-MHS subjects were soldiers, we hypothesize that military duty could select subjects with infraclinical myopathy and therefore would increase the MHS:EHS subject ratio.

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