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- Z Kocak, H Akay, S Gucenmez, A Tufan, and O Donderici.
- Infectious Diseases & Clinical Microbiology Department, Ankara Research & Training Hospital, Ankara, Turkey. drzeliha@hotmail.com
- J Clin Pharm Ther. 2008 Aug 1;33(4):451-2.
AbstractColchicine is widely used, primarily for the treatment of gouty arthritis and familial Mediterranean fever. Colchicine intoxication is a rare but potentially life-threatening event. Herein, we reported a 26-year-old woman who presented to the emergency department after ingesting 27.5 mg of colchicine in a suicide attempt. She exhibited signs typical of colchicine-poisoning and developed infectious complications but with subsequent complete recovery. This paper discusses the role of colchicine poisoning in increasing susceptibility to infections. This aspect is usually under-appreciated in the clinical picture of colchicine overdose.
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