• Respir Physiol Neurobiol · Mar 2012

    Review

    Pulmonary mechanics during mechanical ventilation.

    • William R Henderson and A William Sheel.
    • Program of Critical Care Medicine, University of British Columbia, Vancouver, BC, Canada. William.Henderson@vch.ca
    • Respir Physiol Neurobiol. 2012 Mar 15;180(2-3):162-72.

    AbstractThe use of mechanical ventilation has become widespread in the management of hypoxic respiratory failure. Investigations of pulmonary mechanics in this clinical scenario have demonstrated that there are significant differences in compliance, resistance and gas flow when compared with normal subjects. This paper will review the mechanisms by which pulmonary mechanics are assessed in mechanically ventilated patients and will review how the data can be used for investigative research purposes as well as to inform rational ventilator management.Copyright © 2011 Elsevier B.V. All rights reserved.

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