• Neuromodulation · Mar 2011

    Role of pretrial systemic opioid requirements, intrathecal trial dose, and non-psychological factors as predictors of outcome for intrathecal pump therapy: one clinician's experience with lumbar postlaminectomy pain.

    • David Kim, Alik Saidov, Vijay Mandhare, and Adam Shuster.
    • Department of Anesthesiology, Henry Ford Hospital, Detroit, MI 48202, USA. dklm1@hfhs.org
    • Neuromodulation. 2011 Mar 1;14(2):165-75; discussion 175.

    ObjectiveNon-psychological parameters may predict pump success.MethodsReview was performed on 35 implants for gender, age, pretrial/trial dose, baseline visual analog scale (VAS), and pain location. One-year outcomes were % change VAS/intrathecal dose and medication change. Spearman coefficients correlated pretrial/trial dose, age, baseline VAS, and % change in VAS/intrathecal dose. Wilcoxon Rank-Sum tests correlated gender/pain location and % change in VAS/intrathecal dose. Pretrial/trial dose, baseline VAS, and medication change was tested using Wilcoxon Rank-Sums. Chi-square was used to correlate medication change with gender/pain location. A two-sample t-test compared age and medication change.ResultsPositive correlation between % change VAS and trial dose was noted. Greater age correlated with lower VAS and % dose change. Marginally significant difference in % dose change by pain location was present with higher doses for leg pain.ConclusionTrial dose, age, and partially pain location are good predictors of pain relief.© 2011 International Neuromodulation Society.

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