• Maria Cristina Volpato, José Ranali, Juliana Cama Ramacciato, Patrícia Cristine de Oliveira, Glaúcia Maria Bovi Ambrosano, and Francisco Carlos Groppo.
• Department of Physiological Sciences, Faculty of Dentistry of Piracicaba, State University of Campinas, São Paulo, Brazil. volpato@fop.unicamp.br
• Anesth Prog. 2005 Jan 1;52(4):132-5.

AbstractThe purpose of this study was to compare the anesthetic efficacy of 2 bupivacaine solutions. Twenty-two volunteers randomly received in a crossover, double-blinded manner 2 inferior alveolar nerve blocks with 1.8 mL of racemic bupivacaine and a mixture of 75% levobupivacaine and 25% dextrobupivacaine, both 0.5% and with 1 : 200,000 epinephrine. Before and after the injection, the first mandibular premolar was evaluated every 2 minutes until no response to the maximal output (80 reading) of the pulp tester and then again every 20 minutes. Data were analyzed using the Wilcoxon paired test and the paired t test. No differences were found between the solutions for onset and duration of pulpal anesthesia and duration of soft tissue anesthesia (P > .05). It was concluded that the solutions have similar anesthetic efficacy.

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